产品货号：
Z37554
中文名称：
EWS/EWSR1抗体
英文名称：
Anti-EWS/EWSR1 Antibody (Clone#4B4)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EWS/EWSR1 Antibody (Clone#4B4) |
| 指标别名 | EWS;EWS oncogene;EWSR1;RNA binding protein EWS |
| 克隆性 | Monoclonal |
| 检验物种 | human,monkey,mouse |
| 应用范围 | WB,IHC |
| 基因名称 | EWSR1 |
| 克隆号 | 4B4 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human EWSR1 (369-399aa NDSVTLDDLADFFKQCGVVKMNKRTGQPMIH),different from the related mouse sequence by one amino acid. |
| 实际分子量 | 95KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | This gene encodes a multifunctional protein that is involved in various cellular processes,including gene expression,cell signaling,and RNA processing and transport.The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain.Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis.These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein.Mutations in this gene,specifically a t(11;22)(q24;q12) translocation,are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors.Alternative splicing of this gene results in multiple transcript variants.Related pseudogenes have been identified on chromosomes 1 and 14. |
| Uniprot ID | Q01844 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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